Thursday, October 19, 2006

Press analyses tablet compression phases

Simulator is a single-punch press used to duplicate and analyse precompression, compression, and ejection phases in industrial tablet-production presses under identical production conditions.

Designed for use in pharmaceutical research laboratories, the STYLCAM 200R Simulator is a single-punch press used to duplicate and analyse precompression, compression, and ejection phases in industrial tablet-production presses under identical conditions to those of a unit producing up to 300,000 tablets/h. It allows the operator to test punches, optimise primary parameters, produce small clinical batches, about 2,500 tablets per hour, and create real prototypes of production batches without stopping manufacturing. Fully automated, the press is an ideal solution for characterizing powder compressibility capacities using just a few grams of the active powder, it can produce a single tablet if required.

Flexible and easy to operate and clean, it uses an oil-less lubrication technology for the punches, has a sealed compression zone, and works with standard tools.

It is equipped with an adjustable mechanical cam connected to a programmable electronic cam.

For analysis, the press uses Analis acquisition and regulation software, which guarantees the accuracy of predictive analyses from the first phase of research.

It is used to set optimum precompression parameters for formulation, to avoid capping, to detect the adhesive forces of new punches, or to choose the best tools for tablets with a break line.

In Bourg en Bresse, France, Medelpharm has a test laboratory where the STYLCAM can be tested.

A team of compression analysis specialists, such as technicians and pharmacists, answer questions asked by laboratories concerning formulation, industrial development and in-process trouble-shooting.

* About Medelpharm - Medelpharm specialises in powder compression, with solutions from research and development to production and maintenance.

Medelpharm designs and produces research presses and its OPTITAB laboratory provides studies, formulations, and other services linked to compression.

Its workshop repairs, renovates, and maintains production presses of all kinds.

Medelpharm will be at the AAPS trade show in Nashville, Tennessee, USA, from November 7 to 9, 2005, at booth 2102.